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Posteromarginal Nucleus Information

The marginal nucleus of spinal cord, or posteromarginal nucleus, or Substantia Marginalis, Rexed lamina I, is located at the most dorsal aspect of the dorsal horn of the spinal cord. The neurons located here receive input primarily from Lissauer's tract and relay information related to pain and temperature sensation. Pain sensation relayed here cannot be modulated, e.g. pain from burning the skin.

Anatomy of torso (primarily): the spinal cord (TA 14.1.02, GA 9.749)
External, dorsal Posterior median sulcus · Posterolateral sulcus
Grey matter/ Rexed laminae
I–VI: Posterior horn I: Marginal nucleus · II: Substantia gelatinosa of Rolando · III+IV: Nucleus proprius · Spinal lamina V · Spinal lamina VI
VII: Lateral horn Intermediolateral nucleus · Posterior thoracic nucleus
VIII–IX: Anterior horn Interneuron · Alpha motor neuron (Onuf's nucleus)
X: Other Central gelatinous substance · Gray commissure Central canal · Terminal ventricle
White matter
somatic/ ascending (blue)

Posterior/PCML: touch: Gracile · Cuneate

Lateral: proprioception: Spinocerebellar (Dorsal, Ventral) · pain/temp: Spinothalamic (Lateral, Anterior) · Posterolateral (Lissauer) · Spinotectal

Spinoreticular tract · Spino-olivary tract
motor/ descending (red) Lateral: Corticospinal (Lateral) · Ep (Rubrospinal, Olivospinal) Anterior: Corticospinal (Anterior) · Ep (Vestibulospinal, Reticulospinal, Tectospinal)
both Anterior white commissure
External, ventral Anterior median fissure · Anterolateral sulcus
External, general Cervical enlargement · Lumbar enlargement · Conus medullaris · Filum terminale · Cauda equina

: CNS

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